Rickettsial pathogens and their arthropod vectors
Fri, 2007-02-02 15:01 — Vince Smith
| Title | Rickettsial pathogens and their arthropod vectors |
| Publication Type | Journal Article |
| Year of Publication | 1998 |
| Authors | Azad, AF, Beard CB |
| Journal | Emerging Infectious Diseases |
| Volume | 4 |
| Pages | 179-186 |
| Journal Date | Apr-Jun |
| Accession Number | 45109 |
| Keywords | Animals; Arthropod Vectors/microbiology ; Dermacentor ; Fleas/microbiology ; Humans ; Pediculus ; Research Support, P.H.S. ; Rickettsia/growth & development ; Rickettsia Infections/epidemiology/microbiology/transmission ; Rocky Mountain Spotte, U.S. Gov't |
| Abstract | Rickettsial diseases, important causes of illness and death worldwide, exist primarily in endemic and enzootic foci that occasionally give rise to sporadic or seasonal outbreaks. Rickettsial pathogens are highly specialized for obligate intracellular survival in both the vertebrate host and the invertebrate vector. While studies often focus primarily on the vertebrate host, the arthropod vector is often more important in the natural maintenance of the pathogen. Consequently, coevolution of rickettsiae with arthropods is responsible for many features of the host-pathogen relationship that are unique among arthropod-borne diseases, including efficient pathogen replication, long-term maintenance of infection, and transstadial and transovarial transmission. This article examines the common features of the host-pathogen relationship and of the arthropod vectors of the typhus and spotted fever group rickettsiae. |
