Activation of Rickettsiae prowazekii in the composition of immune complexes by antiglobulin serum
Fri, 2007-02-02 15:01 — Vince Smith
| Title | Activation of Rickettsiae prowazekii in the composition of immune complexes by antiglobulin serum |
| Publication Type | Journal Article |
| Year of Publication | 1989 |
| Authors | Klimchuk, ND, Frolov AF, Shablovskaia EA, Sagaidakovskii NN, Gavrilov SV |
| Journal | Mikrobiologicheskii zhurnal |
| Volume | 51 |
| Pages | 61-63 |
| Journal Date | May-Jun |
| Accession Number | 45363 |
| Keywords | Animals; Antibodies, Anti-Idiotypic/immunology ; Antigen-Antibody Complex/immunology ; English Abstract ; Lice/microbiology ; Rickettsia prowazekii/immunology |
| Abstract | The antiglobulin serum (AGS) against spotted fever immunoglobulin of guinea pigs was studied for its effect on the in vitro created immune complex rickettsiae + antibody in experiments using the procedure of laboratory cultivation of Rickettsiae prowazekii according to Weigl. The biological activity of the pathogen is shown to be restored under the action of AGS. This fact may be used for detecting the antigen + antibody complexes in case of the spotted fever and for studying their role in the relapsive forms of the disease. |
