<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Huelsenbeck, J. P.</style></author><author><style face="normal" font="default" size="100%">Rannala, B.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phylogenetic methods come of age: testing hypotheses in an evolutionary context</style></title><secondary-title><style face="normal" font="default" size="100%">Science</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals; Base Sequence; DNA; Evolution; Evolution</style></keyword><keyword><style  face="normal" font="default" size="100%">Molecular; Hantavirus; Lice/genetics; Likelihood Functions; Mutation; Phylogeny; RNA</style></keyword><keyword><style  face="normal" font="default" size="100%">Non-U.S. Gov't; Research Support</style></keyword><keyword><style  face="normal" font="default" size="100%">P.H.S.; Rodentia/genetics</style></keyword><keyword><style  face="normal" font="default" size="100%">U.S. Gov't</style></keyword><keyword><style  face="normal" font="default" size="100%">Viral/genetics; Research Support</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1997</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Apr 11</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">276</style></volume><pages><style face="normal" font="default" size="100%">227-232</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">The use of molecular phylogenies to examine evolutionary questions has become commonplace with the automation of DNA sequencing and the availability of efficient computer programs to perform phylogenetic analyses. The application of computer simulation and likelihood ratio tests to evolutionary hypotheses represents a recent methodological development in this field. Likelihood ratio tests have enabled biologists to address many questions in evolutionary biology that have been difficult to resolve in the past, such as whether host-parasite systems are cospeciating and whether models of DNA substitution adequately explain observed sequences.</style></abstract><issue><style face="normal" font="default" size="100%">5310</style></issue><accession-num><style face="normal" font="default" size="100%">45141</style></accession-num><notes><style face="normal" font="default" size="100%">0036-8075Journal</style></notes></record></records></xml>